Ciclopirox Olamine Cream

Generic name: Ciclopirox Olamine

Drug class: Broad-spectrum antifungal agent.

Common formulations: topical cream (e.g., 0.77%), lotion, solution.

Usage: For superficial fungal infections of skin (such as ringworm, jock itch, athlete’s foot) and in some cases nail infections.

✅ Indications (kab use karein)

Skin fungal infections: e.g.

Tinea pedis (athlete’s foot)

Tinea cruris (jock itch)

Tinea corporis (ringworm on body)

Nail fungal infection (onychomycosis) for topical solution form.

⚠️ Mechanism of Action (kaise kaam karta hai)

Ciclopirox olamine works by chelating metal ions (Fe³⁺ or Al³⁺) in fungal cells, which inhibits metal-dependent enzymes needed for fungal survival.

Also may disrupt fungal cell membrane, intracellular transport, DNA repair and cell division. It also has some anti-inflammatory properties.

🧪 Dosage & Administration

For topical cream (0.77%): Apply twice daily (morning & evening) to affected skin + surrounding area.

For nail infection solution: Usually apply once daily at bedtime after trimming nails.

Important: Even if symptoms improve, complete full course is necessary to avoid recurrence.

Storage: Store at room temperature. Keep out of reach of children.

🚫 Contra-indications & Precautions (kab na use karein / savdhaani)

Avoid use if hypersensitivity (allergy) to ciclopirox or any excipient.

Do not apply in eyes, inside mouth, nose, vagina unless instructed.

Pregnancy & breastfeeding: Use only if clearly needed and under medical supervision.

Children: Safety in younger age groups may not be established for all formulations.

⚠️ Side-effects

Common: Local irritation — redness, burning, itching at application site.

Less common but serious: Blistering, swelling or oozing at treated area — if these occur, stop use and consult doctor.